Take into consideration alternant therapies that aren't average CYP3A inducers throughout remedy with mitapivat. If unable to avoid coadministration, keep track of Hb and titrate over and above fifty mg BID, if important, but don't exceed mitapivat dose of 100 mg BID. .

pentobarbital will lessen the extent or result of repaglinide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.

pentobarbital will decrease the level or result of prednisone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.

Workout caution every time a barbiturate is administered to the nursing woman; compact amounts of barbiturates are excreted inside the milk

pentobarbital will decrease the level or effect of levoketoconazole by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unknown.

Contraindicated (1)pentobarbital will lower the extent or effect of roflumilast by impacting hepatic/intestinal enzyme CYP3A4 metabolism.

pentobarbital will decrease the extent or impact of elagolix by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

pentobarbital will lessen the level or impact of ramelteon by influencing hepatic enzyme CYP2C9/10 metabolism. get more info Minor/Importance Mysterious.

Contraindicated (1)pentobarbital will decrease the extent or influence of doravirine by affecting hepatic/intestinal enzyme CYP3A4 metabolism.

pentobarbital will decrease the level or outcome of dexamethasone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.

pentobarbital will minimize the level or influence of triazolam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.

pentobarbital will reduce the extent or influence of rabeprazole by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unfamiliar.

pentobarbital will lower the extent or result of pioglitazone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Not known.

pentobarbital will minimize the extent or impact of voriconazole by affecting hepatic enzyme CYP2C9/10 metabolism. Slight/Importance Unidentified.